UCLA Endocrinology

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RESEARCH PAPERS

A. Research Papers - Peer reviewed

1. De Vil, Ch., and Van Herle, A.J. "Een ongewone verwikkeling bij een geval van colitis ulcerosa." J. Flemish Assoc. of Gastroenterology, part 6, Number 4, (1963).

2. Fevery, J., Van Herle, A.J., Brucher, J.M., and Vanderbroucke, J. "Spierziekten:Vier gevallen van Dystrophia myotonica." Belgisch Tydschrift voor Geneeskunde 1:14-30 (1967).

3. Steeno, O., Heyns, W., Van Baelen, H., Van Herle, A.J., and De Moor, P. "Urinary steroid excretion in normal pubertal boys." Eur. J.Steroids2:273-80 (1967)

4. Van Herle, A.J., Steeno, O., Heyns, W., Hendrickx, A., and De Moor, P. ''Adrenocrortical and gonadal function in fat adolescent boys." Eur. J. Steroids 2:283-95 (1967).

5. Kantor, G.L., Van Herle, A.J., and Barnett, E.V.Auto-antibodies of the IgD class." Clin. Experi. Immuno. 6:951-62 (1970).

6. Van Herle, A.J., and Chopra, I.J. "Thymic hyperplasia in Graves' disease." J. Clin. Endocrinol. Metab. 32:140-46 (1971).

7. Miller, T., Bernstein, J., and Van Herle, A.J. "Cushing's syndrome cured by resection of appendiceal carcinoid." Arch. Surq. 103:770-73 (1971).

8. Van Herle, A.J., and Uller, R.P. "T3 thyrotoxicosis: A recently recognized entity. A case report and review of the literature." Acta. Clin. Belgica 27:516-20 (1972)

9. Davidson, M.B., Van Herle, A.J., and Gerschenson, L.E. "Insulin and sepharose insulin effects on tyrosine transaminase levels in cultured rat liver cells." Endocrinology 92:1442-46 (1973).

10. Van Herle, A.J., Uller, R.P., Matthews, N.L., and Brown, J. "Radioimmunoassay for measurement of thyroglobulin in human serum. H J. Clin. Invest. 52:1320-27 (1973).

11. Xhonga, F.A., and Van Herle, A.J. "The influence of hyperthyroidism on dental erosions." Oral Surg., Oral Med. and Oral Path. 36:349-57 (1973).

12. Uller, R.P., Van Herle, A.J., and Chopra, I.J. Comparison of alterations in circulating thyroglobulin, triiodothyronine an thyroxlne in response to exogenous (Bovine) and endogenous (human) thyrotropin. J. Clin. Endocrinol. Metab. 37:741-45 (1973).

13. Glinoer, D., Puttemans N., Van Herle, A.J., Camus,M.and Ermans, A.E. "Sequential study of the impairment of thyroid function in the early states of subacute thyroiditis." Acta Endocr mol. 77:26 (1974).

14. Van Herle, A.J., Young, R.T., Fisher, D.A., Uller, R.P., and Brinkman, III, C.R. "Intra-uterine treatment of a hypothyroid fetus." J. Clin. Endocrinol. Metab. 40:474-77 (1975).

15. Van Herle, A.J., and Uller, R.P. "Elevated serum thyroglobulin: A marker of metastases in differentiated thyroid carcinoma." J. Clin. Invest. 56:272-77 (1975).

16. Lippe, B.M., Van Herle, A.J., LaFranchi, S.H., Uller, R.P., Lavin, N., and Kaplan, S.A. "Reversible hypothyroidism in growth hormone-deficient children treated with human growth hormone." J. Clin. Endocrinol. Metab., 40:612-18 (1975).

17. Van Herle, A.J., Klandorf, H., and Uller, R.P. "A radioimmunoassay for serum rat thyroglobulin. Physiologic and pharmacological studies." J. Clin. Invest. 56:1073-81 (1975)

18. Reza, M.J., Young, R.T., Van Herle, A.J., DeQuattro, V., Cole,H.S., and Brown, J. "Multiple endocrine adenomatosis type II (Sipple's syndrome) in twins." West. J. Med. 123:441-46 (1975).

19. Young, R.T., Van Herle, A.J., and Rodbard, D. "Improved diagnosis and management of hyper-and hypothyroidism by timing the arterial sounds." J. Clin. Endocrinol. Metab., 42:330-40 (1975).

20. Shimaoka, K., Van Herle, A.J., and Dindogru, D. "Thyrotoxicosis secondary to involvement of the thyroid with malignant lymphoma." J. Clin. Endocrinol. Metab., 43:64-68 (1976).

21. Van Herle, A.J., Chopra, I.J., Hershman, J.M., and Hornabrook, R.W. "Serum thyroglobulin in inhabitants of an edemic goiter region of New Guinea." J. Clin. endocrinol. Metab. 43:512-16 (1976).

22. Uller, R.P., Van Herle, A.J., and Chopra, I.J. "Thyroidal response to graded doses of bovine thyrotropin." J. Clin. Endocrinol. Metab., 45:312-18 (1977).

23. De Groot, L.J., Hoye, K., Refetoff, S., Van Herle, A.J., and Rochman, H. "Serum antigens and antibodies in the diagnosis of thyroid cancer." J. Clin. Endocrinol. Metab., 45:112 (1977).

24. Uller, R.P., and Van Herle, A.J. "The effect of therapy on serum thyroglobulin levels in patients with Graves' disease." J. Clin. Endocrinol. Metab., 46:747-55 (1978).

25. Honbo, K.S., Van Herle, A.J., and Kellett, K. "Serum prolactin levels in untreated primary hypothyroidism." Am. J. Med. 64:782-87 (1978).

26. Ruiz-Velasco, R., Waisman, J., and Van Herle, A.J. "Cystic papillary carcinoma of the thyroid gland: Diagnosis by needle aspiration with transmission of electron microscope." Acta Cytologica 22:38-42 (1978).

27. Van Herle, A.J., Orgiazzi, J., Greipel, M.A., Slucher, J.A., and Honbo, K.S. "Immunoreactive TSH in urinary concentrates of Graves' disease patients: A radioimmunoassay artifact." Eur. J. Clin. Invest. 8:295-201 (1978).

28. Levine, G.A., Hershman, J.M., Van Herle,A.J., and Deftos, L.J. "Thyroglobulin and calcitonin in patients with nontoxic goiter." JAMA 240:2282-83 (1978).

29. Lee, W.N.P., Golden, M.P., Van Herle, A.J., Lippe, B.M., and Kaplan, S.A. "Inherited abnormal thyroid hormone-binding protein causing selective increase of total serum thyroxine." J. Clin. Endocrinol. Metab. 49:292-99 (1979).

30. Unger, J., Boeynaems, J.M., Van Herle, A.J., Van Sande, J., Rocmans, P., and Mockel, J. "In vitro non-butanolextractable iodine release in dog thyroid slices." Endocrinology 105:225-31 (1979).

31. Chopra, I.J., Van Herle, A.J., Chua Teco, G.N., and Nguyen, A.H. "Serum free thyroxine in thyroidal and nonthyroidal illnesses: A oomparison of measurements by radioimmunoassay, equilibrium dialysis and free thyroxine index." J. Clin. Endocrinol. Metab. 51:135-43 (1980).

32. Unger, J., Van Heuverswyn, B., Decoster, C., Cantraine, F., Mockel, J., and Van Herle, A.J. "Thyroglobulin and thyroid hormone (T4, T3) release following intravenous administration of bTSH in man." J. Clin. Endocrinol. Metab. 51:590-94 (1980).

33. Ashcraft, M.W., and Van Herle, A.J. "Thyroid Nodule: Medical management." Head Neck Surg. 3:216-20 and 297-322 (1981).

34. Van Herle, A.J., Demeester-Mirkine, N., and Van Heuverswyn, B. "The effect of 131I for diagncstic purposes on serum thyroglobulin (hTg)levels in subjects with thyroidal disorders." J. Endocrinol. Invest. 4:107-110 (1981).

35 .Van Herle, A.J., Panagiotis, N., Naruse, R., Freisleben, L, and Van Herle, H,M-L. "Orphenadrine citrate (Norflex) mediated inhibition of thyroid function in the adult male rat." J. Endocrinol. Invest. 4:141-48 (1981).

36. Ashcraft, M.W., and Van Herle, A.J. "The comparative value of serum thyroglobulin measurements and 131Iodine total body scans for the follow-up of patients with treated differentiated thyroid cancer." Am. J. Med. 71:806-14 (1981).

37. Schlumberger, M., and Van Herle, A.J. "Critical analysis of 131I and 125I human thyroglobulin (Tg) labels for radioimmunoassay (RIA) use." J. Clin. Endocrinol. Metab. 54:581-86 (1982).

38. Schlumberger, M., and Van Herle, A.J., Di Paola, R., Vignal, A., Di Paola, M., Kahn, E., and Tubiana, M. "In vivo localization of radiolabelled antibodies to rat thyroglobulin in the l-lC2 rat thyroid transplantable tumor." Nucl. Med. Comm 3:4-12 (1982).

39. Ashcraft, M.W., Van Herle, A.J., Vener, S., and Geffner, D. "Serum cortisol levels in Cushing's syndrome after low and high dose dexamethasone suppression." Ann. Int. Med. 97:221-226 (1982).

40. Pardridge, W.M., Van Herle, A.J., Naruse, R.T., Fierer, G.H., and Costin, A. "In vivo quantification of receptor-mediated uptake of asialoglycoproteins by rat liver." J. Biol. Chem. 258:990-94 (1983).

41. Ashcraft, M.W., Hartzband, P.I, Van Herle, A.J., Bersch, N., and Golde, D.W. "A unique growth factor in patients with acromegaloidism." J. Clin. Endocrinl. Metab. 57:272-76 (1983).

42. Hershman, J.M., Due, D.T., Sharp, B., My, L., Kent, J.R., Bihn, L.N., Reen, A.W., Phuc, L.D., Van Herle, A.J., Thai, N.A., Troung, T.X., Van, N.V., Sugawara, M., and Pekary, A.E. "Endemic Goiter in Vietnam." J. Clin. Endocrinol. Metab., 57:243-49 (1983).

43. Sakiyama, R., Ashcraft, M.W., and Van Herle, A.J. "Cyclic Cushing's syndrome." Am. J. Med. 77:944-46 (1984).

44. De Keyser, L., Layfield, L., Van Herle, A.J., Costin, A., and Lewin, K. "Biochemical and immunohistochemical characterization of proteins in Hurthle cell carcinoma." J. Endocrinol. Invest. 7:449 (1984).

45. Hartzband, P.I., Diehl, D., Lewin, K.J., and Van Herle, A.J. "Histologic characterization of a lingual mass using thyroglobulin immunoperoxidase staining." J. Endocrinol. Invest. 7:221-223 (1984).

46. Van Herle, A.J., Van Herle, I.S., and Greipel, M.A. "An international cooperative study evaluating serum thyroglobulin standards." J. Clin. Endocrinol. Metab. 60:338-343 (1985).

47. Geffner, M.E., Lippe, B.M., Bersch, N., Van Herle, A.J., Kaplan, S.A., Elders, M.J., and Golde, D.W. "Growth without growth hormone: Evidence for a potent, circulating human growth factor." Lancet 1:343-347 (1986).

48. Smallridge, R.C., De Keyser, L., Van Herle, A.J., Butkus, N.E., and Wartofsky, L. "Thyroid iodine content and serum thyroglobulin: Cues to the natural history of destruction induced thyroiditis." J. Clin. Endocrinol. Metab. 62:1213-1219 (1986).

49. Costin, A., Perselin, J.E., Klandorf, H., and Van Herle, A.J. "Characterization of high titer human anti-Tg autoantibcdies." J. Endocrinol. Invest. 10:541 (1987).

50. Birnbaum, J., Klandorf, H., Giuliano, A., Van Herle, A.J. "Lithium stimulates the release of human parathyroid hormone in vitro ." J. Clin. Endocrinol. Metab. 66:1187-1191 (1988).

51. Hartzband, P., Van Herle, A.J., Sorger, L., and Cope, D. "Assessment of hypothalamic-pituitary-adrenal (HPA) axis dysfunction: Comparison of ACTH stimulation, insulin-hypoglycemia and metyrapone." J. Endocrinol Invest 11:769-776 (1988).

52. Estour, B., Van Herle, A.J., Juillard, G.J.F., Sparkes, R.S., Giuliano, A.E., and Klandorf, H. "Characterization of a human follicular thyroid carcinoma cell line (UCLA RO 82 W-l)." Virchows Archiv B Cell Pathology 51:167-174 (1989).

53. Birnbaum, J., and Van Herle, A.J. "Immunoheterogeneity of parathyroid hormone in parathyroid cysts: Diagnostic implications." J. Clin Endocrinol Invest 12:831-836, (1989).

54. Birnbaum, J., Giuliano, Al, and Van Herle, A.J. " Partial adrenalectomy for pheochromocytoma with maintenance of adrenocortical function." J. Clin Endocrinol Metab 69(5):1078-1081 (1989).

55. Van Herle, A.J., Rosenblitt, P.D., Van Herle, T.L., Greipel, M.A., and Kellett, K.A. "Immunoreactive thyroglobulin (Tg) and anti-Tg antibodies (TgAb) in serum and saliva of patients with various thyroid disorders. Role of Autoantibodies." J. Endocrinol Invest 12:177-182 (1989).

56. Van Herle, A.J., Agatep, M.L., Padua III, D.N., Totanes, T.L., Van Herle, H., and Juillard, J. "Effects of 13-cis Retinoic Acid on growth and differentiation of human follicular carcinoma cells in vitro." J Clin Endocrinol Metab 71(3):755-763 (1990).

57. Narhi, D.C., Huberman, A.K., De Keyser, L., Furst, D.E., Ross, R., Clements, P.J., and Van Herle, A.J. "Thyroid dysfunction in progressive systemic sclerosis: Results of a prospective study." J Endocrinol Invest 13:161-169 (1990) .

58. Van Herle, A.J., Estour, B.,Juillard, G., Giuliano, A., Hawkins, R.A., and Van Herle, K. "In vitro and in vivo binding of labeled immunoglobulin aggregates to a human malignant thyroid tumor cell line: Implications for immunocytochemical studies and in vivo immunodetection of tumors." J. Endocinol. Invest:14:635-646 (1991).

59. Salzler, M.J., Van Herle, A.J., Varki, N.M., Tillisch, J. "Endocardial metastases of follicular thyroid carcinoma: A case report and review of literature." Eur J Surg Onc 17:219-223 (1991).

60. Fain, J.S., Naeim, F., Becker, D.P., Van Herle, A.J., Yan-Go, F., Petrus, L. and Vinters, H.V. "Chronic lymphocytic leukemia presenting as a pituitary mass lesion." Can. J. Neurol. Sci. 19:239-242 (1992)

61. Gross, C., Yu, M., Van Herle, A.J., Giuliano, A.E., and Juillard, G.J.F., "Presence of a specific antiestrogen binding site on human follicular thyroid carcinoma cell line (UCLA RO 82 W-1): inhibition by endogeneous ligand present in human serum." J. Clin. Endocrinol Metab. 77:1361-1366 (1993).

62. Chopra, I., Van Herle, A.J., Korenman, S., Younai, S. "Use of sodium ipodate in management of hyperthyroidism in subacute thyroiditis." J. Clin. Endocrinol. July (1995).

63. Bailey J, Chopra I, Lewin K, Van Herle AJ. "Pituitary mass as a manifestation metastatic thyroid carcinoma." Thyroidol. Clin. Exp. 7:23-28 (1995).

64.. Feldt-Rasmussen, U., Profilis, C., Colinet, E., and Tg-standardization group. "Human thyroglobulin reference material (CRM 457). 1. Assessment of homogeneity, stability, and immunoreactivity." Ann. Biol. Clin. 54:337-342 (1996)

65. Feldt-Rasmussen, U., Profilis, C., Colinet, E., and Tg-standardization group. "Human thyroglobulin reference material (CRM 457). 2. Physicochemical characterization and certification." Ann. Biol. Clin. 54:343-348 (1996).

66. Yu, M., Lin, J.D., Giuliano, A.E., Juillard, G.J.F., Van Herle, K. A-M, and Van Herle, A.J.. "Estrogen and progesterone receptor expression and E2-regulated cell proliferation in four human thyroid cancer cell lines." Thyroidology Clinical and Experimental.

67. Yu, M., Van Herle, H.M., Lin, J.D., Giuliano, A.E., Van Herle, A.J.. "Differences in PTH (1-84) release in response to ambient calcium concentrations of parathyroid adenoma fragments and dispersed parathyroid adenoma cells in culture." J. Endocrinol. Invest. 19:342-347 (1996).

68. Kelemen PR, Van Herle AJ, Giuliano AE. "Sentinel Lymphadenectomy in Thyroid Malignant Neoplasms. Archives Surg. 133: 288-292 (1998)

69. Goodman WG, Veldhuis JD, Belin TR, Van Herle AJ, Tuppner H, Salusky IB. "Calcium-sensing by the para thyroid glands in secondary hyperparathyrodism. J. Clin Endocrinol Metab. (In Press) (1998).

70. Van Herle AJ, Birnbaum L.A, Slomowitz D, Mayes DW, Chandler PD, Rosenblit PD, Nissenson A. "Paper chromatography prior to cortisol RIA allows for accurate use of the dexamethasone suppression test in chronic renal failure." Nephron 1:79-84 (1998)

71. Bailey J, Van Herle AJ, Giuliano A, Schroder S. Unilateral adrenal medullary hyperplasia: another form of curable hypertension? Int J Clin Pract. 53: 149-151 (1999)

72. Yin F, Giuliano AE, Van Herle AJ. "Growth Inhibitory effects of flavonoids in human thyroid cancer cell lines." Thyroid. 9: 369-376 (1999)

73. Mark O. Goodarzi and Andre Van Herle. Thyrotoxicosis in a male patient associated with excess human chorionic gonadotropin production by germ cell tumor. Thyroid. Vol. 10, Number 7, 611-618, (2000)

B. Research Papers - Peer Reviewed - In Press:

Yin F, Giuliano, AE, Van Herle AJ.  "Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells."  (ARO) Anticancer Research Vol. 19: 4297-4304, (1999)

P. Cohan, S. Hirschowitz, J. Yu Rao, S. Tanavoli, and A. J. Van Herle. Amyloid goiter in a case of systemic amyloidosis secondary to ankylosing spondylitis. Journal of Endocrinological Investigations. Vol. 23, ( 2000)

C. RESEARCH PAPERS - PEER REVIEWED (SUBMITTED)

1. Lin, J.D., Yu, M., Juillard, G.J.F., Giuliano, A.E., Van Herle, A.J. "Thyralbumin (TA): A Thyronine (T3, T4) binding protein synthesized by differentiated and poorly differentiated thyroid cancer cells." ( submitted for publication)

2. Yu, M., Van Herle A.J., Van Herle, K., Juillard, G.J.F., Giuliano, A.E. "Ethanolic extracts of normal human serum affect the proliferation of human thyroid carcinoma cell lines in vitro." (submitted for publication)

D. RESEARCH PAPERS - NON-PEER REVIEWED

1. Van Herle AJ, Clinical utilization of tumor markers in thyroid cancer. Thyriodology (Clinical and experimental) 11:5-8, 1999

CHAPTERS

1. Pearlman, J.T., Saxton, J., and Van Herle, A.J. Retinitis pigmentosa: Accelerated course of visual loss secondary to exogenous thyroid administration. In: Retinitis Pigmentosa (1976). (ed. M.B. Landers, III, M.L. WoIbarsht, J.E. Dowling and A.M. Laties.) Plenum Publishing Corp., New York, page 223.

2. Van Herle, A.J. and R.P. Uller. Thyroid Cancer. Classification, Chemical Features, Diagnosis and Therapy. In: International Encyclopedia of Pharmacology and Therapeutics (1977). (ed. J.M. Hershman and G. Bray.) Pergamon Press Ltd., Oxford, England, Vol. 2, pp 215-138.

3. Van Herle, A.J. Thyroid Disease. In: Endocrinology Pathophysiology.Patient-Oriented Approach (1977). (ed. J.M. Hershman.) Lea & Febinger, pp 39-78

4. Van Herle, A.J. Serum thyroglobulin assay. In: Radiation,Associated Thyroid Cancer (1977). (ed. L.J. DeGroot.) Grune & Stratton, Inc., pp 329-337.

5. Van Herle, A.J. Thyroid gland malignancies method of. In: Current Therapy (1978). (ed. H.J. Conn), p. 495.

6. Van Herle, A.J. Pathophysiology of thyroid cancer. In: Thyroid Cancer (ed. L.D. Greenfield.) CRC Press (1978), Chapter 2, pp 23-36.

7. Dumont, J.E., F.J. Malone, and A.J. Van Herle. Irradiation and thyroid disease: dosimetric, clinical and carcinogenic (1980). Commission of the European Communities, Brussels Catalogue #CN-NJ-80-001-EN-C.

8. Van Herle, A.J. Thyroid Nodules and Thyroid Cancer. (ed. H. Carlson.) John Wiley & Sons (1983), pp 73-92.

9. Van Herle, A.J., and K.A-M. Van Herle. Advances in Endocrinology. In: Current. Medicine. (ed. G.L. Gitnick.) John Wiley L Sons (1983), New York. Chapter 8, pp 217-233.

10. De Keyser, L., and A.J. Van Herle. Hypothyroidism. In: Current Diagnosis. (ed. R.B. Conn). W.B. Saunders Co. (1985), pp 840-843.

11. Van Herle, A.J. Circulating Thyroglobulin in Thyroid Cancer. In: Progress in Endocrine Research and Therapy, Vol. 2. (eds. M.C. Eggo and C.N. Burrow.) Raven Press (1985), New York, pp 317-323.

12. Van Herle, A.J. Thyroid tumors. In: Manual of Endocrinology and Metabolism (ed. Norman Lavin.) Little Brown. (1986), New York, pp 379-388.

13. Van Herle, A.J. Measurement and clinical significance of thyroglobulin in serum and body fluids. In: The Thyroid. (eds. S. Ingbar and L. Braverman.) J.B. Lippincott Oo., (1986) Philadelphia, PA, pp 524-545.

14. Van Herle, A.J. Thyroglobulin synthesis and metabolism: Clinical aspects. Proceedings of the Henning symposium, Thieme Verlag, Homburg/Saar West Germany 1985.

15. Van Herle, A.J., Brown D.G. Thyroglobulin in Benign and malignant Thyroid disease In: Thyroid disease. Endocrine Surgery, Nuclear Medicine and Radiotherapy. (ed. Stephen A. Falk.) Raven Press (1990), New York, pp 473-484.

16. Van Herle A.J. Clinical test of thyroid function in: The thyroid gland. (ed. Monte A. Greer.) Raven Press, New York Chapter 12: 345-390 (1990)

17. Van Herle, A.J. Measurement and clinical significance of thyroglobulin in serum and body fluids. In: The Thyroid. (eds. L. Braverman and R. Utiger.) J.B. Lippincott Co. (1991), Philadelphia, PA.

18. Van Herle, A.J., Lutz, A.T,-Differentiated Thyroid carcinoma. In: Thyroid diseases. Clinical fundamentals and therapy. ( Eds. F. Monaco, M.A. Satta, B Shapiro, and L. Trocone-CRC Press Inc. 1993)

REVIEWS

A. PEER REVIEWED

1. Brown, J., Chopra, I.J., Cornell, J.S., Hershman.,J.M., Solomon, D.H., Uller, R.P. and Van Herle, A.J. "Thyroid physiology in health and disease." Ann. Int. Med., 81:68-81 (1974)

2. Brown, J., Solomon, D.H., Beall, G.H., Terasaki, P.I, Chopra, I.J, Van Herle, A.J., and Wu, S. "Autoimmune thyroid disease - Graves' and Hashimoto's." Ann. Int. Med., 88:379-91 (1978).

3. Van Herle, A.J., Vassart, G., and Dumont, J.E. "Control of thyroglobulin synthesis and secretion." Medical Progress, N. Engl. J. Med. 301:239-49 and 307-14 (1979).

4. Van Herle, A.J. "Serum thyroglobulin measurement in the diagnosis and management of thyroid disease." Thyroid Today 4:2 (1981).

5. Van Herle, A.J., Rich, Pl, Ljung, B-M, E., Ashcraft, W.M., Solomon, D.H., and Keeler, E.B. "The Thyroid Nodule." Ann. Int. Med. 96:221-232 (1982).

6. De Keyser, L., and Van Herle, A.J. "Differentiated thyroid cancer in children." Head & Neck Surgery 8:100-114 (1985).

7. McMullen, G.R. and Van Herle, A.J. "Hirsutism and the effectiveness of Spironolactone in its management." J. Endocrinol. Invest. 16:925-932, (1993).

B. NON-PEER REVIEWED

1. Van Herle, A.J. "Serum thyroglobulin levels in patients with differentiated thyroid carcinoma." Ann. de Radiologie, 20:743-45 (1977).

2. Van Herle, A.J., Van Heuverswyn, B., and Vassart, G. "Interet clinique du dosage de la thyroglobulin serique." Rev. Med. Brux. 1:5-8 (1980).

3. Van Herle, A.J. "Serum thyroglobulin in benign thyroid diseases and thyroid malignancies." Exp. Clin. Endocrinol. 102:83-86, (1994).

4. Van Herle, A.J. "Glands and Hormones." The World Book Health and Medical Annual. 300-301 (1995).

PAPERS IN PREPARATION (RESEARCH COMPLETED)

1. Burford, P.A., Van Herle, A.J., Kingston, E. "Clinical utility of ultrasound guided fine needle aspiration biposies (FNAB) of thyroid nodules."

2. Zielke, A., Tezelman, S., Jossart, G., Van Herle, A.J., Siperstein, A.E., Clark, O.H., Duh, Q.Y. "TSH and EGF stimulate thyroglobulin secretion and invasion of a metastatic Hurthle cell carcinoma cell line.

ABSTRACTS

1. Van Herle, A.J., T. O'Neill and J. Brown. Experimental thyroiditis in hamsters. Western Section, Am. Fed. Clin. Res. Vol. XVII, 1969.

2. Newbould, B.B., A.J. Van Herle, C.M. Pearson and V. Van deSande. Allergic thyroiditis in rats. Passive Transfer and Effects of Lymphadenectomy at intervals after active induction. Presented at the Autumn meeting of the British Society for Immunolcgy on 10/23/69, London, England.

3. Van Herle, A.J., and Chopra I.J. Graves' disease and thymic hyperplasia. 45th American Thyroid Assoc. Meeting, Chicago, Ill, Ncvember 13-15, 1969.

4. Kantor, G.L., Van Herle, A.J. and Barnett, E.V. IgD antinuclear (ANA) antithyroid (ATA) and antiglomerular basement membrane (AG-BM) antibodies (AB). American Rheumatism Assoc. Meeting, Tucson, Arizona, December 1969.

5. Kantor, G.L., Van Herle, A.J. and Barnett, E.V. IgD antibodies in systemic lupus erythematous (SLE), thyroidits and renal disease. Presented at the Western Section American federation for Clinical Research." Clin. Res. 18-135, 1970.

6. Bernstein, J., Van Herle, A.J., Jacobson, S. and Brown. J. Cushing's syndrome cured by appendectomy. Western Section, American Federation for Clinical Research. Clin. Res. 18-120, 1970.

7. Uller, R.P., Van Herle, A.J., Matthews, N.L. and Brown, J. Serum thyroglobulin levels in healthy subjects and thyrotoxic patients. Abst. #315, J. Clin. Invest. 50:94a, 1971.

8. Uller, R.P. and Van Herle, A.J. TSH stimulated thyroglobulin release in man. Presented at the 47th American Thyroid Assoc. Meeting, Birmingham, Alabama, 1971.

9. Van Herle, A.J., and Uller, R.P. A radioimmunoassay for circulating human thyroglobulin. Presented at the IV International Congress of Endocrinology, " ,Washington D.C., 1972.

10. Young, R.T., Van Herle, A.J. and Darryl M. Elevated serum gonadotropin after unilateral orchiectomy for an estrogen secreting tumor. IV International Congress of Endocrinology, Washington , D.C. 1972.

11. Davidson, M.B., Gerschenson L.W. and Van Herle, A.J. Studies with Sepharosebound insulin on muscle, adipose tissue and cultured liver cells. Diabetes 21:335, 1972.

12. Uller, R.P., and Van Herle, A.J. Biochemical analysis of thyroid cyst content. Annual Meeting of the Amer. Thyroid Assoc., Chicago, Ill, 1972.

13. Young, R.T., and Van Herle, A.J. Discrepancy between circulating thyroid hormone concentrations and myocardial contractility. Presented at European Thyroid Assoc., Jerusalem, 1972.

14. Uller, R.P, Van Herle, A.J. and Chopra, I.J. Cbmparison of alterations in circulatinq thyroglobulin (Tg) triiodothyronine (T3) and thyroxine (T4) in response to exogeneous (bovine) and endogenous (human) and thyrotropin (TSH) Clin. Res. 21:206, 1973

15. Van Herle, A.J., and Xhonga, F.A. Incidence of dental erosions in hyperthyroidism. Clin. Res. 21:2026 1973.

16. Young, R.T., and A.J. Van Herle. Estimation of thyroid function by a measure of myocardial contractility. Clin. Res. 21:256, 1973.

17. Uller, R.P., A.J. Van Herle, and I.J. Chopra. The effect of exogenous (bovine) and endogenous (human) thyrotropin (TSH) and thyroxine (T4). Presented at the Annual meeting of the Endocrine Society, Chicago, Ill, 1973.

18. Uller, R.P., and A.J. Van Herle. Effect of therapy on serum thyroglobulin in patients with Graves' disease. Presented at the Annual meeting of the Am. Thyroid Assoc., Seattle, Washington, 1973.

19. Lippe, B.M., A.J. Van Herle, R.P. Uller, S. LaFranchi, S.A. Kaplan. Reversible hypothyroidism developing during HGH therapy. Presented at the Am. Thyroid Assoc., Seattle, Washington , 1973.

20. Glinoer, D., N. Puttemans, and A.J. Van Herle. Sequential study of iodine metabolism impairment in the early stages of subacute thyroidits. Presented Eoropean Thyroid Assoc. Meeting, Jerusalem, 1973.

21. Uller, R.P. and A.J. Van Herle. Predictive value of serum thyroglobulin concentratian in the outcome of therapy in patients with Graves' disease. Am. Fed. for Clin. Res. (Abst) 1973.

22. Van Herle, A.J., and R.P. Uller. Serum thyroglobulin (Tg): A sentsitive marker of thyroid carcinoma and its metastases. Presented Am. Fed. Clin. Res. Meeting, Atlantic City, 1974.

23. Van Herle, A.J., and R.P. Uller. Serum and pleural fluid thyroglobulin (Tg): A sensitive marker of thyroid carcinoma and its metastases. Presented at The Endocrine Society Meeting, Atlanta, 1974.

24. Chopra, I.J., S.R. Smith and A.J. Van Herle. Serum thyroid hormone and thyrotropin (TSH) levels in protein-calorie malnutrition (PCM). Submitted Am. Thyroid Assoc., 1974.

25. Van Herle, A.J., H. Klandorf, and R.P. Uller. Radioimmunoassay for the measurement of serum thyroglobulin (rTg) in the rat. Presented Am. Fed. Clin. Res., Carmel, 1975.

26. Rodbard, D., R.T. Young and A.J. Van Herle. Monitoring therapy of hyper- and hypo-thyroidism by sphgmorecording; The QKd time interval. Submitted International Thyroid Association meeting, Boston, 1975.

27. Shimaoka, K., A.J. Van Herle, and A. Dindogru. Thyrotoxicosis associated with lymphomatous involvement of the thyroid. Submitted Endocrine Society, 1975.

28. Degroot, L.J., S. Refetoff, A.J. Van Herle, R.P. Uller, H. Rochman and K. Hoy. Serum antigens and natibodies in diagnosis of thyroid cancer. Presented Endocrine Society, New York, 1975.

29. Honbo, K. and A.J. Van Herle. Serum prolactin levels in untreated primary hhypothyroidism. Clin. Res. 25:130A, 1976.

30. Van Herle, A.J. and R.P. Uller. Effect of therpay on serum thyroglobulin levels in patients with Graves' disease. Eur. Thyroid Assoc., Lyon, France, Sept. 1977.

31. Van Herle, A.J., J. Orgiazzi and K.S. Honbo. Immunoreactive TSH in urinary concentrates of Graves' disease patients: A radioimmunoassay artifact. Eur. Thyroid Assoc., Lyon, France, September 1977.

32. Denney, J.D., R. Marty and A.J. Van Herle. Serum thyroglobulin A sensitive indicator of metastatic well differentiated thyroid carcinoma. Soc. Nucl. Med. 2nd Ann. West. Reg. Metg. Oct. 1977, Las Vegas.

33. Honbo, K.S., A.J. Van Herle, and J.J. DiStefano, III. Peripheral metabolism of thyroglobulin in the rat. Clin Res. 26:106A, 1978.

34. Honbo, K.S., A.J. Van Herle, and J.J. DiStefano, III. Peripheral metabolism of thyroglobulin in the rat. 60th Annual Meeting, The Endocrine Society 1978 (Abst 692).

35. Morgan, D.F., C. Angelini, R.A. Pieter Kark, A.R. Nissenson, J.R. Bentson, A.J. Van Herle, and B. Adornato. Unusual spinocerebullar degeneration associated with short stature and neurogenic diabetes insipidus. Am. Acad. Neurol. 1978.

36. Ashcraft, W.M., A.J. Van Herle, S.L. Vener, and D. Geffner. Assessment of adrenal function using serum dehydroepiandrosterone-sulfate (DHEA-S) and serum cortisol levels in normal and subjects with Cushing's syndrome. 61st annual Meeting, Endocrine Society, 1979, Abst. 644.

37. Van Herle, A.J., N. Panagiotis, R. Naruse, L. Freisleben, and H.M-L Van Herle. Orphenadrine citrate (Norflex) mediated inhibition of thyroid function in the adult male rat. (Submitted VIII International thyroid Congress, Sydney, Austr. 1980).

38. Ashcraft, M.W., M.A. Greipel, K.A. Kellett, J.A. Slucher, and A.J. Van Herle. Comparison of serum thyroglobulin and total body radioiodine scans for detection of well-differentiated thyroid carcinoma after ablative therapy. Presented at the 62nd Annual Meeting fo the Endocrine Society, 1980.

39. Lee, W.N-P, M.E. Geffner, S.A. Kaplan, B.M. Lippe, A.J. Van Herle, M.D. Harpen. Hypothyroxinemia of the premature neonate: A new method of assessment. Western Soc. Ped. Res. Carmel, California, Clin. Res. 29:110A, 1981.

40. Ashcraft, M.W, Van Herle AJ, Bersch N, Golde DW.  A new growth stimulating factor in patients with pseudoacromegaly.  Endocrine Society, Cincinnati, Ohio, 1981.

41. Schlumberger, M., and A.J. Van Herle. Critical analysis of 13lI and 125I human thyroglobulin labels for radioimmunoassay use. 11th Congress of the ETA meeting, Pisa, Italy, 1981.

42. Ashcraft, M.W., A.J. Van Herle, and D.W. Cope. Effects of diphenyldhydantoin on gonadotropin and thyrotropin release in Klinefelter'syndrome. Clin. Res. 29:26a, 1981.

43. Lee, W.P., A.J. Van Herle, M.D. Harpen and D. Aron. Purification of a new thyroxine binding protein. Western Soc. Ped. Res., Carmel, California, Clin. Res. 1982.

44. Pardridge, W.M., R.N. Naruse, and A.J. Van Herle. In vivo uptake of asialoglycoprotein by rat liver: A model of in vivo plasma protein clearance. Western Section Am. Fed. Clin. Res., Carmel, California, Clin. Res. 1982.

45. Pardridge, W.M., R.N. Naruse, G. Fierer, and A.J. Van Herle. In vivo quantification of hepatic asialoglycoprotein receptors. Am. Soc. Clin. Invest., May 1982.

46. Hershman, J.M., D.T. Due, B. Sharp, J.R. Kent, A.W. Reed, A.J. Van Herle, and A.E. Pekary. Endemic goiter in Vietmnam. Am. Thyroid Assac. Meetings, se}~I3l~er 1982 (Canada).

47. Hershman, J.M., D.T. Due, B. Sharp., L. My, H.R. Kent, L.N. Binh, A.W. Reed, L.D. Phuc, A.J. Van Herle, N.A. Thai, T.X. Troung, N.V. Van, M. Sugawara, and A.E. Pekary. Endemic Goiter in Vietnam. Assoc. Am. Physicians. Clin. Res. 1982.

48. Ross, R.R., A.L. Fymat, W.N.P. Lee, M.A. Greenfield, P.J. Clements, D.E. Furst, and A.J. Van Herle. In vivo thyroid function studies in progressive systemic sclerosis (PSS). Soc. Nucl. Med., 30th Annual Meeting, St. Louis, Mo., 1983.

49. De Keyser, L., L. Layfield, A.J. Van Herle, A. Costin, and K. Lewis. Biochemical and immunohistochemlcal characteristics of proteins in Hurthle cell carcinoma. Endocrine Society, 65th Annual Meeting, San Antonio, Texas, 1983.

50. Lee, W.H., M.D. Harpen, L. De Keyser, A. Costin, and A.J. Van Herle. Familial euthyroid hyperthyroxinemia (FEH): Demonstration of two thyroxine binding albumins. Endocrine society, 65th Annual Meeting, San Antonio Texas, 1983

51. Huberman, A.K., D.C. Narhi, L. De Keyser, R. Ross, P.J. Clements, D.E. Furst, and A.J. Van Herle. Thyroid function in progressive systemic scleroeis (PSS): A prospective study. Am. Rheumatism Assoc. Meetings, San Antonio, Texas, 1983.

52. Hershman, J.M., D.T. Due, B. Sharp, L. My, J.R. Kent, L.N. Binh, A.W. Reed, L.D. Phuc, A.J. Van Herle, N.A. Thai, T.X. Troung, N.V. Van, M.Sugawara, and A.E. Pekary. Endemic goiter in Vietnam. Clin. Res. 31:527A, 1983.

53. Huberman, A.K., D.C. Narhi, L. De Keyser, R. Ross, P.J. Clements, D.E. Furst, and A.J. Van Herle. "Thyroid function in progressive systemic sclerosis (PSS): A prospective study. Am. Thyroid Asscc. Meeting, New Orleans, La. 1983 (Accepted for presentation).

54. Hartzband, P., L. Sorger, and A.J. Van Herle. Recovery of the hypothalamicpituitary adrenal (HPA) axis following chronic steroid therapy. Presented at the 7th annual Congress of Endocrinology, Quebec, Canada, 1984.

55. Geffner, M.E., B.M. Lippe, N. Bersch, A.J. Van Herle, S.A. Kaplan, and D.W. Golde. Growth in a child without growth hormone (GH): Evidence for a potent growth factor. Presented at the 67th Annual Meeting of Endocrine Society, Baltimore, 1985.

56. Costin, A., and A.J. Van Herle. Characterization of high titer human anti-Tg autoantibodies. 9th International CongressThyroid Association Meeting, Sao Paulo, Brasil, Abst #43, September 1985.

57. Smallridge, R.C., L. De Keyser, A.J. Van Herle, N.E. Butkus, and L. Wartofsky. Thyroid iodine content, serum thyroglobulin, and perchloarte d1scharge tests in destruction induced thyroiditis. Presented at the 9th International Congress, Thyroid Association Meeting, Sao Paulo, Brasil, Abst #99, September 1985.

58. Rosenblitt, P.D., J. Brown, S. Levin, H.J.L. Frank, A.J. Van Herle. Visceral protein malnutrition is coincident with non-ketotoic hyperosmolar hyperglycemla. Clinical Research Meeting, Carmel. February 4-7, 1986.

59. Estour, B., G. Juillard, A. Giuliano, T. Totanes, B. Cheng, H. Klandorf, and A.J. Van Herle. Characterization of a human follicular thyroid carcinoma cell line WRO 82-1. 68th Annual meeting of The Endocrine Society, Anaheim, CA, June 1986.

60. Rosenblitt, P.D., J. Brown, S. Levin, H.J.L. Frank, and A.J. Van Herle. Hypersmolar hyperglycemic non-ketotic state coexists with viseral protein malnutrition. Annual meeting of the American Diabetes Association, 1986.

61. Rosenblitt, P.D., and A.J. Van Herle. Hydrocortisone suppression test in a patient suspicious of Cuhsing's syndrome on chronic hemodialysis. 68th Annual Meeting of The Endocrine Society, Anaheim, CA, June 1986.

62. Estour, B., A.J. Van Herle, G. Juillard, A. Giuliano, and R.A. Hawkins. In vitro and in vivo binding of labelled immunoglobulin aggregates to a malignant human thyroid cell line: Implicatians for in vivo immunodetection of tumors. Soc. Nucl. Med. 34th Annual Meeting, Toronto, June 1987 (Abst. #652).

63. Estour, B., A.J. Van Herle, G. Juillard, A. Giuliano, and R.A. Hawkins. Binding of labeled immunoglobulin aggregates to human thyroid tumor cells "in vitro" and in transplanted xenografts: The role of immunoaggregates in immunodetection. Am. Am. Thyroid Assoc. September 16-19, 1987, Washington D.C..

64. Birnbaum, J.A., H. Klandorf, A.E. Giuliano, and A.J. Van Herle. Lithium, increases parathyroid hormone relase from human parathyroid tissues in vitro. Clin. Res. Meeting, February 16, 1988. Carmel, CA.

65. Van Herle, A.J., Agatep, M.L., Padua, D.N., Canlapan, D.V., Totanes, T.L., Juillard, G. "Effect of 13-cis Retinoic Acid (13-cis RA) on the proliferation and differentiation of human follicular cancer cells in vitro." Abstract 57. 63rd American Thyroid Association Meeting, Montreal, Sept. 1988 (Accepted for presentation).

66. Birnbaum, J.A., Van Herle, A.J., Mayes, D., Nissenson, A. Paper chromatography prior to cortisol RIA allows accurate use of the dexamethasone suppression test in chronic renal failure. Endocrine Society Meeting, Seattle Washington, 1989.

67. Van Herle, A.J., Agatep, M.L., Padua D.N., Canlaplan D.V., Totanes T.L. and Juillard G. Effect of 13 cis RA on the proliferation and differentiation of human thyroid cancer cells. 18th European Thyroid Association Meeting Copenhagen-Denmark, July 1989 (accepted for presentation).

68. Van Herle, A.J., Yu, M., Gross, C., Giuliano, A.E., and Juillard, G.J.F. Presence of an anti-estrogen in ethanolic extracts of human serum; extracts inhibit the growth of thyroid cancer cells in vitro. American Thyroid Association Meeting, Tampa, Florida, 1993.

69. Burford, PA, Van Herle, AJ, Kingston, E. Clinical utility of ultrasound guided fine needle aspiration biopsies (FNAB) of thyroid nodules. Abstract accepted for presentation. American Thyroid Association Meeting, Chicago, Ill., 1994.

70. A Zielke, S. Tezelman, G. Jossart, T. Hoelting, A.J. Van Herle, A.E. Siperstein, O.H. Clark, Q.Y. Duh. TSH and EGF stimulate thyroglobulin secretion and invasion of a metastatic hurthle cell carcinoma cell line. Abstract accepted for presentation. American Thyroid Association Meeting , Chicago, Ill., 1994.

71. Kelemen, A.J. Van Herle, A.E. Giuliano. Sentinel lymphadenectomy in thyroid malignancy. John Wayne Cancer Institute, Santa Monica, CA, and Section of Endocrinology, UCLA Medical Center.

72. Van Herle, A.J. Clinical utilization of tumor markers in thyroid cancer. Biomed and Pharmacothera. Vol 52-331, 1998.

73. Yin, F. and Van Herle, A.J. Antiproliferative effects of flavonoids on human thyroid carcinoma cell lines. American Thyroid Association Meeting. Portland, Oregon, 1998

74. Yin F, Giuliano AE, Van Herle AJ. "Signal pathways involved in apigenin inhibition of growth and induction of human anaplastic thyroid cancer cells." (ARO) Anticancer Research Vol 19: 4297-4304, 1999.

75. Kafaja S, Van Herle AJ. The role of ultra sound-guided fine needle aspiration biopsy (USFNAB) in the management of thyroid nodules. Journal of Investigative Medicine 42:22A, 1999.

76. Yin, F., Guiliano, A.E., Law, R.E.and Van Herle A.J. Apigenin inhibits growth and inducesG2/M arrest by modulating cyclin-CDK regulators and MAP Kinase activation in breast, carcinoma. 91st Annual Meeting American Association for Cancer Research (AACR), San Francisco, CA . 2000

 

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